Overview
Nintedanib is a small molecule tyrosine kinase inhibitor including the receptors platelet-derived growth factor receptor (PDGFR) α and β, broblast growth factor receptor (FGFR) 1-3, and VEGFR 1-3.
Nintedanib is a small molecule kinase inhibitor used primarily to treat various forms of progressive, scarring lung diseases. It works by inhibiting multiple receptor tyrosine kinases, reducing the cellular signals that cause tissue fibrosis.